If your had a motorcycle in the 1950's, 60's and early 70's, your only choice was wire wheels. Nobody whinged about flat tires.
All off-road bikes are still built with laced wheels. No whingers there either. In fact, they know that catastrophic, irreparable damage is far more likely on a cast wheel than on a laced one: the latter can be made serviceable with a rock and a tube patch, and you'll be able to ride out to civilization. Try that on a cast wheel with tubeless tire.
My first bike--bought in 1969--was a 1964 Triumph. It was my sole transportation, throughout college and beyond, on both coasts. Never had a flat. Never worried about it.
Every bike in my current stable has the laced wheels it came with: 1968 Triumph Bonneville and 1970 Triumph Trophy, (both ridden 10's of thousands of miles--including coast to coast trips--since I bought them around 1980.) No flats, no anxiety on the Dunlop wire wheels.
My main rides now are my 2005 Moto Guzzi California Vintage and my 2013 Moto Guzzi 750 Racer. I have been on many long distance (two to three thousand miles, round trip) rides on those bikes with no flats and no fear. (Annoyingly frequent tire changes though, due to wear--both even and uneven--and not the fault of my beautiful Borrani wheels.)
And, FWIW, I have never had to adjust the spokes on any of my bikes! I've tested my runout and spoke tension occasionally, but never found any need to break out the spoke wrench. (However, I have recently restomodded my Trophy as a cafe racer. I built the wheels myself, using stainless rims, spokes, and nipples. So I know how to lace and true a wire wheel.)
What else? Well, here is a partial list--just off the top of my head--of brand new bikes street bikes (similar in market to the RE 650's) that come with wire wheels standard:
Triumph--various Models--indeed, almost all the "classic " models
Moto Guzzi--exactly half the 18 model lineup comes with laced wheel and tubed tires
Kawasak-- WD 800
Various HD Heritage models
And of course, every model of RE has laced wheels
Lastly, if you really need to stress about flats, instead of swapping your wheels, why get a motorcycle rider on your AAA membership? It'll cost a whole lot less, and you'll get a free 100 mile tow. If that cant help you with your tire, I don't know what will.