If I can be permitted to jump in about your question, the answer is yes, you can just do the barrel/piston, or you could do barrel/piston/cam, and an EFI tune to suit.
That can be done.
However, there are certain things to be expected from certain mods, in terms of engine behavior.
With a big bore kit and tune, the basic result will be much higher compression, resulting in higher torque/hp thru much of the rpm range, but the rpms for peak tq and peak hp will be somewhat lower than before. The overall rev range will be shifted downward due to bigger displacement being served by the same breathing capacity as before.
So yes, more tq and hp at the revs you can still reach, but lower max rpms than before. More of a puller than a revver.
Add a cam, and it can make up some of those lost rpms by providing more breathing time for the cylinder to fill, even if the head still is unmodified.
Add some port modification, and the revs and power curve can climb higher yet, due to more flow into the cylinder during the time allotted by the cam.
And each stage would need its own tune.
You can take it to whatever stage you want, but you should be aware of the effects you get at each stage. These are just basic descriptions given, but are intended to provide general expectations from certain mod stages.
Hope that helps.
Obviously, I don't intend to be the only responder to the question, and I look forward to hearing what others may have to say on the topic.