My money is on Putin in the Ukraine and Taiwan "reunified" with the PRC by March whilst the "free" world stands by, indulging in an orgy of self immolation driven by social media "patriots" & complicit GOP/Right Wing Vichy leadership. That's the important outcome to avoid. If the vaccine is actually a trojan horse, anyone associated with Big Pharma won't be able to step outside their compound again without springing a leak; this is Amurrika where virtually everyone has a deer rifle & long memory. Biden went out of his way to say no more lockdowns to avoid personally initiating CWII, in the face of the viral-spread countermeasures being taken by our offshore allies. The evening news is now describing Chinese hypersonic ship killing weaponry (poorly), there are geopolitical maps on the news showing Russian armour & troops surrounding the Ukraine, and another long article about how much explosives & ordinance the Army & other services have "lost track" of, apparently redirected to Alt-Reich groups. Meanwhile the entire GOP leadership is still lip-synching for the Trump Qanon crowd, still whinging about stolen elections, still banging on about removing college level classes from grade schools that don't exist and being supported by wide eyed, very vocal Qanon fed parents. We have weekly mass shootings by nut cases raised on "First Person Shooter" games and conspiracy websites. The capacity for the USA to rub two coherent thoughts together for our collective survival doesn't look too encouraging to me. Whatever come next will be really ugly, really stupid & utterly avoidable.
I don't think that worrying about possible adverse vaccine side effects in a country as litigious & well armed as the USA compares in urgency; that horse has left the barn. Our main concern needs to be making rational choices & presenting a unified front to the foreign agencies deliberately sowing dissent. Broken can be mended. Managing a process takes rational thought & hard work. The only folks benefitting by letting things burn to the ground are scrap dealers & insurance fraudsters.