I've done Albuquerque, NM to Aurora, CO a few times now with the C5. about 1200m round trip, with one overnighter each way. Took a couple days off in Aurora before the returns. No problems other than a loose bar end weight. Definitely add some extra days, bring the spare tubes, fuses, VOM, a few rags, a bit of assorted hardware, some stainless wire, and any/all of the above suggestions. Whatever you do, don't push it or yourself, and stay hydrated.
A long trip on a bike will wear you out quickly compared to a cage.