I suppose a Royal Enfield Ensign engine/transmission (1953-1958) might be just about a direct drop in for the Prince engine/transmission (1959-1962), as far as the frame is concerned.
The internal parts would probably be different though.
"Royal Enfield The Complete Story" by Mick Walker ©2003 says on page 65, 66,
"New for 1959, the Prince, although still a 158cc two-stroke, differed in several ways from the Ensign.
In the engine, circular flywheels were employed in place of the former bob-weights, and as a result, crankcase compression was raised, providing an increase in power - 7.5bhp at 4,750 rpm (against 6bhp at the same engine revolutions). To cope with the extra power, the gearbox (still a three-speeder) features a beefed-up mainshaft and improved pinion tooth form; while a neoprene synthetic rubber shock absorber was incorporated in the sprocket on the gearbox mainshaft..."
By the way, the Ensign was also sold as the " Lance", (1957-1959) during the years that many Royal Enfields were sold in the USA carrying the "Indian" motorcycle badge.
Unfortunately, many of the people who own these Indian badged motorcycles think they are worth a fortune just because of the Indian name.