Hi.
Break-in: big opinion swings here, but I would suggest doing some research. I have found that breaking in an engine by being gentle with it is a great way to glaze your cylinders and never get good compression. IMHO, an engine should be run in according to how it's going to be used. I can provide some good URL's that show blow-by and piston condition, side by side, of engine's broken in "the gentle way" and engine's broken in according to normal use. I have found that by breaking in my engines normally, I get fewer problems down the road with blow-by and compression.
Oil: synthetic or dino, the important thing is not to use a detergent oil. Oils with detergent additives do exactly that: clean off the carbon deposits that you actually want to have helping seat the rings. This is absolutely critical to getting your engine to run well over the long term.
The first fluid changes are the important ones. Get to them as close to the recommended mileage as you can. After that, a few extra miles won't hurt.
happy riding!
c