Well, had a mostly successful freeway run on Saturday. Went from Indianapolis to Columbus, OH and back. 175 miles one-way via I-70. So, 350 miles total. It went pretty well short of shedding my toolbox cover and toolkit unbeknownst to me. I had removed it and replaced it the night before, but had locked it and tugged on it to ensure it was snug. The locking mechanism and everything obviously vibrated loose. All I was left with was a shell of a toolbox. Frustratingly, my registration and insurance card were also in the toolbox. I have an extra insurance card, registration can be replaced, and fortunately new parts are cheap. I just feel a little sheepish that, at some point, the dang thing rattled off onto the highway and I didn't even know.
Other than that, the bike handled pretty good. I had to ask my fellow riders to slow down a bit. Also, my speedo needle started bouncing +/- 5 mph. I'm hoping the cleaning/lubing of the speedo cable and retightening is all that is needed. I am feeling like I'm having some clutch issues, which I'll post separately in another thread.
As a summary, this bike (C5) is freeway capable. It may not be without quirks and maintenance issues, but it'll do the requisite speed and distance. I got good mileage for this bike at 70 mph. Averaged about 67 mpg. Really, the only uncomfortable part was my butt.